Skeletal muscles combust both lipids and carbohydrates during exercise. The carbohydrates consist of both glycogen stored in the muscles as well as glucose extracted from the blood. Being a major sink for glucose disposal, skeletal muscle represents an important model tissue for studying the intracellular signaling pathways leading to increased glucose transport.

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"I love you like a fat kid loves cake". Some lovesick rapper wrote these words of wisdom for a woman who was just a jail cell away. But it's true. We fat kids do love our cake. Rather, we "smooth perpetual bulkers" do love our carbs. And there’s nothing wrong with that. Carbohydrates are a terrific source of energy, and an essential building block of life. But, like all things in life, you CAN have too much of a good thing. And that quickly becomes a bad thing – insulin resistance.

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