A:  It's a significant supplement on the market today because it is unlike anything out there. Now, keep in mind, that doesn't mean it's better or worse than what's currently out there, just different. That's because Celadrin is a blend of acetylated fatty acids, esters and other synergistic agents that enhance cell membranes throughout the body, which results in more normalized joint function. Unlike other NSAIDs, like Ibuprofen, that just mask joint discomfort, Celadrin targets the source by enhancing cell membranes and restoring vital fluids (Synovial fluid is what is found in the joint capsule) that cushion joints.  The esterified fatty acids in Celadrin spark positive changes at the cellular level and make cell membranes much more responsive and less prone to articular cartilage deterioration. The success of this supplement, is as a result of how easily absorbed and bioavailable the ingredients are. Quite literally, you can see results within 30 minutes of taking Celadrin, by way of improved joint mobility and support. It's available in oral or topical cream, but unless you use DMSO to carry the Celadrin through the skin and into the joint, transdermally, it's likely that the oral form is going to be more effective. We would actually say that Celadrin is a nice complement to Glucosamine/ Chondroitin and MSM. The action of the glucosaminaglycans found in most joint supplements is much different than the action of fatty acids.